Wednesday, July 31, 2019

Bosnian Refugee Life in America Essay

Thousands of refugees from Bosnia-Herzegovina have fled to the United States to seek protection from the ethnoreligious conflicts of the region. To best assist these families, service providers must understand their wartime and migration experiences and their culture. The purpose of this article is to review the literature relevant to working with Bosnian Muslim refugees as well as to understand the uruque issues facing this population. The authors’ interest in Bosnian Muslim refugees is a personal one. Between 1992 and 2001, nearly 3,500 Bosnian refugees escaping ethnic cleansing and war migrated to Bowling Green, a small city of 50,000 in rural southcentral Kentucky. The Bowling Green International Center has been a part of the local community since 1979 and actively works with the United States Committee for Refugees and Immigrants (USCRI). For more than 25 years, the center has assisted thousands of refugees of many nationalities in their migration to the United States and the local community. According to the center’s director, Marty Deputy, Bosnians make up the largest percentage of refugees that have relocated to Bowling Green (personal communication, February 3, 2005). Deputy also indicated that while Bosnian refugees have adapted well to the local community, they still face many challenges because of their experiences in Bosnia in addition to their integration into a new culture. One of the issues that continue to haunt many Bosnian refugees is post-traumatic stress—a result of war and genocide. Post-traumatic stress is particularly an issue for the adult women, who experienced the trauma of rape and sexual assault as well as witnessing the murder of their children and spouses. According to Deputy (personal communication, February 3, 2005), social workers should approach Bosnian families and children with cultural competence. If visiting a Bosnian home, for example, removing one’s shoes when entering is a display of respect and sensitivity. A willingness to drink a strong cup of Bosnian coffee is also appreciated. Social workers also must be sensitive about body language and speech tone. It is also important not to assume that all Bosnians are alike. As with all cultures, there is tremendous variation in the Bosnian culture, along with individual differences in personality and environmental experiences. Bosnian Muslim Experiences in the War The 1991 census for Bosnia-Herzegovina shows that Muslims made up 43. 7% of the total population of 4. 3 million people. Serbs accounted for 31. 3% and Croats 17. 3% (Bringa, 1995). Serbs identified the Muslims’ majority population base in Bosnia-Herzegovina as its strategic strength (Cigar, 1995). In 1992, therefore, the Serbs declared war and began a campaign of ethnic cleansing to eradicate non-Serbs. The term â€Å"ethnic cleansing† stands for the policy of ridding an area of an undesirable national group to create a homogenous region; it represents a type of genocide that is designed to spread terror (Friedman, 1996; Weine & Laub, 1995). Serbia’s initial rationale for its policy was promulgated by the belief that the newly formed state of Bosnia-Herzegovina would create national minorities of the Serb population and eventually destroy the Serb populace as a discrete and unique nation (Friedman, 1996). The prospect of acquiring material goods from the Muslims—land, livestock, houses, cars, and cash—apparently was an additional powerful incentive for many Serbs (Cigar, 1995; Sells, 1998). The indigenous Bosnian Serb population was drawn into a terror campaign of killing and mayhem so the non-Serbian populations would never return. This persecution ultimately led to more than one million Balkan refugees migrating to the United States and other countries. The types of experiences they endured in their homeland before emigrating dramatically influenced their initial adaptation to these new environments. Resettlement and Adaptation Issues As difficult as the war-related experiences were, migration to resettlement countries signaled a transition to new types of struggles for Bosnian refugees. Unlike immigrants who leave their homes for a variety of reasons, refugees leave in order to survive, and they face a new realm of stressors as they attempt to rebuild their lives in exile (Keyes, 2000; Worthington, 2001). Such stressors include difficult transit experiences; culture shock; adjustment problems related to language and occupational change; and disruption in their sense of self, family, and community (Lipson, 1993; Worthington, 2001). Additionally, refugees leaving Bosnia-Herzegovina often have suffered multiple losses, such as severance from family and friends who have been left behind or killed, displacement from their homes and communities, social isolation, and the premature death of their children. Such an accumulation of loss can leave a sense of unresolved grief that can significantly impact mental health and future functioning capacity (Akhtar, 1992; Fullilove, 1996; Sundquist & Johansson, 1996; Worthington, 2001). When refugees cross national boundaries seeking asylum, they typically find themselves in an alien social environment with norms that challenge their traditional patterns of family interaction (Mayadas & Segal, 2000). Most Bosnian refugees have a hierarchical familial power structure and clear role definitions; in the homeland, authority was typically gender-based, with males maintaining instrumental roles and females fulfilling nurturing responsibilities. A traditional Bosnian woman’s commitment to her family includes observing strict codes of privacy and public silence on any issue that might bring shame on the family, such as family discord. For many women, this privacy mandate deters them from divulging details about marital strife or child maltreatment by spouses to outsiders such as work colleagues, community members, and mental health professionals. Consequently, Bosnian female refugees continue to be caught between traditional role models prevalent throughout the former Yugoslavia’s patriarchal society in the 20th Century and the expectations of their new culture. The Bosnian family’s patriarchal patterns of behavior tend to be challenged on arrival in the United States, particularly around work-related issues. Women are more likely than men to find jobs in the low-wage labor market, and in becoming the breadwinners exposed to the outside world, they risk upsetting a family equilibrium based on male authority (Mayadas & Segal, 2000). For Bosnian men, key ethnic and social boundary markers of their lives had evaporated; because of their grief over this, many seemed paralyzed in their attempt to move forward in their new life. Bosnian refugee children also face immense acculturation pressures (Mayadas & Segal, 2000). They often are torn between the beliefs, customs, and values learned in their native culture and the often unrealistic expectations of the new one. The pressure to assimilate the cultural norms of their new country can be intense and extremely stressful. Their parents often lack the material resources and support systems to adequately assist them in navigating the complex terrain of foreign school systems, pervasive racism, and intolerance (Mayadas & Segal, 2000). Consequently, many feel as if they are alone in a foreign, sometimes unforgiving new cultural milieu. To further complicate the situation, family roles often reverse as children typically become more fluent in English faster and adapt more quickly to the customs of the new country (Potocky, 1996). Because children are thrust into the role of serving as the interpreters and negotiators of cultural norms for their parents, respect for the authority of elders is often undermined (Carlin, 1990; Drachman; 1992). Even though most teenagers in the United States feel a certain amount of intergenerational tension, the adolescents of refugees often experience the pull of two vastly different worlds: those of their American peers and their parents (Mayadas & Segal, 2000). They also feel subjected to the xenophobia of their American peers, who often ridicule others who they label as â€Å"different. † Immigration to the United States has provided Bosnian Muslim refugee families with many challenges as they struggle to adapt to their new lives. At first glance, their experiences may be similar to that of other immigrants, raising the familiar questions about how to perpetuate the faith of their forebears among their offspring or how to best preserve cherished cultural practices (Yazbeck- Haddad & Esposito, 2000). But there are some real differences. With the attacks on the World Trade Center in New York City and the Pentagon in Washington, DC, the potential for a xenophobic reception of Muslim immigrants and refugees by Americans has intensified. For example, disputes over the building of mosques represent a key source of friction for most Westerners (Pipes & Duran, 1993). While Bosnian Muslim families may encounter the same issues earlier generations of immigrants faced, they also are burdened with the question of whether their children will be accepted in the United States, and whether Islam can ever be recognized as a positive force that contributes to a pluralistic, multicultural nation (Yazbeck-Haddad & Esposito, 2000). Culturally Competent Practice with Bosnian Muslims When working with Bosnian Muslim refugees, service providers need to learn as much as possible about their culture, particularly given the pivotal role that ethnoreligious identity has played in their war-related experiences (Witmer & Culver, 2001). Bosnian men and women tend to adhere to traditional gender roles; connected with this issue is the intense stigma attached to the sexual violation of women. This stigma frequently led women to refrain from disclosing war rapes to their families (Witmer & Culver, 2001). Bosnian Muslims typically act in ways that preserve the positive image of the family’s identity, especially males, who see openly revealing vulnerability or suffering as a sign of great personal weakness (Weine et al. , 1997). Family is the most important social structure across the urban and rural regions of Bosnia (Mojica-Castillo, 2001). Up until the 1970s, adult children commonly lived with their parents and multiple generations lived in the same house. But today, twoparent families predominate in this region with extended family members often living nearby. A cluster of shoes can typically be found outside a Bosnian home (Mojica-Castillo, 2001). This is because it is customary to remove street shoes and leave them at the door. Bosnians maintain a strong social tradition of neighborliness. The drinking of strong coffee or the sharing of food, accompanied by the essential element of lively conversation, is an important aspect of social life. Traditional music and folk dances are an important part of cultural celebrations. A basic principle of generalist social work is that practitioners need to be able to intervene on behalf of various systems, including individuals, families, orgaruzations, and communities. Additionally, the generalist social worker operates within an ecological framework that attempts to improve coping patterns for a better match between the client system’s needs and the characteristics of his or her environment. An empowerment approach to generalist practice assumes that clients can draw from existing competencies and reservoirs of strength. Empowerment indicates the intent and the processes of assisting client systems to discover and expand the tools and resources around them (Furuto, 2004). Swift and Levin (1987) referred to empowerment as an evolution from dependence to independence and interdependence. Gutierrez (1990) described empowerment as â€Å"the process of increasing personal, interpersonal, or political power so that individuals can take action to improve their life situations† (p. 140). The strengths perspective enhances the concept of empowerment with its focus on promoting healing. Healing implies both wholeness and the inborn ability of the mind and body to resist and regenerate when faced with disruption, disorder, or disease (Furuto, 2004). Ethnic and religious identity may lead to discrimination when the refugee is seeking a job that requires intervention on a more personal level. Long-term difficulty in finding a job that provides the family with adequate income may cause low self-esteem and family tension culminating in violence (Furuto & Murase, 1992). Various system levels often must be addressed simultaneously (Mayadas & Segal, 2000). Western thinking on designing comprehensive mental health services is mostly based on the individual as the primary system targeted for intervention; hence, existing services tend to be designed for a North American population (Mooren & Kleber, 1999). Furthermore, treatment of mental health disorders typically follows a medical model using talk therapy and drugs. Western theories also emphasize intrapersonal processes in isolation from the cultural context. The prevailing view that the responses to trauma are individual centered is in keeping with this tradition. Service providers must use the refugees’ own, indigenous cultural definitions of health and illness when making mental health assessments (Boothby, 1996; Wing Sue, Ivey, & Pedersen, 1996). For example, a Bosnian client who had the Western diag nosis of major depression and post-traumatic stress disorder â€Å"refused medication saying that there was nothing wrong with him that medications could fix, and insisted that the clinician understand that his current condition was a result of the wrongs that had been done to him, and not because of anything that was wrong with him† (Weine & Laub, 1995, p. 255). To address the issue of respecting the client’s definition of the issue, Yuen (1999) promoted a more holistic biopsychosocial model of intervention when working with Bosnian children and their families; hence, the importance of using an ethnically sensitive ecological framework becomes a second principle of culturally competent practice. A third principle is to respect the indigenous strengths and resources within Bosnians that empower them to cope with their own experiences. Chow & Yuen (2000) noted the necessity for an empowerment and capacity building model where refugees become partners in the design and elivery of services within their community. Efforts to design and deliver human service programs should include using indigenous Bosnian religious and cultural organizations, as well as self-help groups (Chow & Yuen, 2000). Conclusion After Bosnians flee their homeland, they need protection in the asylum country. This necessitates supportive policies and macrolevel intervention competence. The main policy that guides refugee resettlement in the United States is Public Law 96-212, the Refugee Act of 1980 (Mayadas & Segal, 2000). Based on the goal of helping refugees achieve economic self-sufficiency as quickly as possible, the act defines self-sufficiency as not receiving welfare benefits (Potocky, 1996). As such, this policy may be ineffective in helping refugees to settle in an optimal manner. To become truly self-sufficient, service providers need to redefine success in more progressive ways, such as helping refugees to effectively deal with resettlement issues relating to acculturation, psychological trauma, and intergenerational conflict—all of which can impede long-term economic self-sufficiency. This new goal requires adequate fiscal resources to develop programs and engage in active community outreach (Mayadas & Segal, 2000). Social services must aspire to restore the psychological health and dignity of these families and children, who have seen the worst side of human nature. Helping them establish a positive self-image is critical to their success. While the genocide of family members and violent acts can never be forgotten, surrounding Bosnian Muslim refugees with a network of positive, supportive services can help them establish a solid foothold in the United States.

Tuesday, July 30, 2019

Analysis Vission and Mission of Coca-Cola Essay

In general, Coca-cola vision guides all members to understand what the company does, how it is done, and who it is done for also keeps the employees focused on the realistic goals of the firm, customers, investors, and other business partners. An effective vision should consists of two component which the first one is a cognitive component; which focuses on outcomes and how the best to achieve it, and the second component is affective component which will helps to motivate people and gain their commitment toward it( Boal and Hooijberg 2001). Base on Coca-cola vision statement show that they apply the affective component which increasing motivation and commitment among their employees, customers and business partners. The six P’s of Coca-cola vision which is People,, Portfolio, Partners, Planet, Profit and Productivity is the guideline to increase motivation and commitment. These six P’s also clearly mention the desirable future target for each component internally and externally of the firm, which is among people (employees), portfolio (product), partners (customers and suppliers), planet (moral obligation), profit and productivity. These visions also challenge all to participate and reach the organization goals. As a good vision, the internal (organizational beliefs and values) as well as external (shared understanding of the market environment) needs to be aligned. Besides, the Coca-cola vision statement also focuses on how the organizational members relate to the vision and shared each others. †¢People: Be a great place to work where people are inspired to be the best they can be. †¢Portfolio: Bring to the world a portfolio of quality beverage brands that anticipate and satisfy people’s desires and needs. †¢Partners: Nurture a winning network of customers and suppliers, together we create mutual, enduring value. †¢Planet: Be a responsible citizen that makes a difference by helping build and support sustainable communities. †¢Profit: Maximize long-term return to shareowners while being mindful of our overall responsibilities. †¢Productivity: Be a highly effective, lean and fast-moving organization This is a good sample of vision statement because it’s not too specific and realistic to achieve by all their members. This vision statement also encourages all members to participate in achieve the vision.

Monday, July 29, 2019

MGMT Assignment Example | Topics and Well Written Essays - 250 words - 1

MGMT - Assignment Example The values play vital role in the actions and reactions of the people in the work place. An intrinsic sense of responsibility ensures understanding and cooperation among the colleagues whether they are their junior or their seniors. The courage and the ambition go a long way in overcoming the conflicting values which may result due the diversity that the work place represents in term of human resource. Managerial leadership within the organizational environment requires creative approach to communicate effectively, especially for resolving workplace conflicts and promoting cross cultural understanding of values. The vast scope of communication, in terms of behavioral pattern, language used and non verbal means of contact are important factors which are extremely relevant in the social interaction. Conscientiousness, extrovert behavior and communication skill of the man are major factors that ultimately decides in his favor in the cut throat competitive professional field. A person, who makes effort to develop better ways of communicating with others in his field, is able to strengthen his professional relationship and facilitate a better understanding that paves way to a success which promises productive outcome.

Sunday, July 28, 2019

Medical School Essays Essay Example | Topics and Well Written Essays - 750 words

Medical School Essays - Essay Example My undergraduate course at the UC-Berkeley, Public Health, has given me thorough exposure to social issues that affect the provision of healthcare. Given the opportunity, I would like to share my expertise with a large, metropolitan city (i.e. inner city). This setting would be ideal for gaining practical medical expertise, due to the thorough exposure to a wide variety of medical needs. Perhaps, more importantly, this opportunity would permit me to develop accountability and autonomy, commensurate with my abilities. Moreover, this setting will allow me to help as many people as possible, especially those in deprived areas who do not have access to proper medical care. Apart from helping them through my medical expertise, I also want to develop them spiritually and morally. Again, this setting would allow me make a difference in more lives. I have a wealth of experience living in an urban setting, which is accounted for by my eight years of residence in San Francisco. During this time, I went to school, worked full-time and engaged in volunteer opportunities. My volunteer experience at the California Pacific Medical Center and the American Red Cross Mobile are noteworthy, because I have seen first hand the suffering that is undergone by the underprivileged, including disease, lack of basic commodities and resources, and even discrimination. My volunteer experience at the American Red Cross Bloodmobile gave me the opportunity to use my proficiency in the Spanish language to help minority blood donors understand and clarify their concerns with medical staff and fellow volunteers. It is also during these experiences that my resolve to pursue a medical career has been reinforced. I feel fulfilled interacting with patients from diverse and multi-cultural backgrounds, and has allowed me to personally witness the existing dis parities in the urban healthcare system. I have

Law of Tort Assignment Example | Topics and Well Written Essays - 1250 words - 1

Law of Tort - Assignment Example Surv conducted surveys in a manner that was negligent and in violation of their contract of service (Spiers 365). GMAC forwarded their claims to the Webb Resolutions Limited. The proceedings initially involved a total of four valuations. Two were solved and two remained in question. The discrepancy arose due to the difference in the E. Surv valuation and the right price valuation. The damage claim in both instances was a total of $ 46,445 plus interest (Sloan 453). When it comes to the discharge of the value’s duty of care, the supplier agreement dated 22nd September in the year 2004 between E. Surv and GMAC, had not been expressed by E. Surv to the surveys. However, was not clear that those terms governed their conduct (Salmond 228). To establish a loss, the defender must have had the responsibility of the duty of care to the lender. This has to be clearly expressed to both parties. In a tort, the duty of care will always be owed to the lender to the surveyor (Osborne 398). Such circumstances should be accompanied by a contract of the engagement under which the surveyor will have a code of conduct under which he can carry out his services. Such a contract should have the expression of the fact that the work is to be carried out with sufficient care and skill (North 234). If the valuation is done in a negligent manner, it will constitute a violation of the contract. If such an event takes place, then the court will have the responsibili ty of stepping in to establish if such clauses are enforceable or reasonable (Mcdeen 338). With regard to the margin of error test, there is a raging debate as to whether attention needs to be paid to the methodology of the surveyor while conducting a valuation or if the focus ought to be on the output of the valuation (Macod 227). The logic behind this argument is that the end justified the means. If an era was made in the methods and procedures used, it is overlooked if the results of the valuation

Saturday, July 27, 2019

Examine the causes of the increase in Somali-led piracy off the Horn Essay

Examine the causes of the increase in Somali-led piracy off the Horn of Africa during the past 5 years - Essay Example years, the threats from the pirates increasing day by day even though international community and UN Security Council have strengthened the counter measures in the Somali coastal areas. Patrolling in the Somali coastal areas have been strengthened by multinational naval force including warships from America, Britain, India and Australia. Anthony Bergin, Director of Research Programs for the Australian Strategic Policy, arguing that the protection of international shipping is of high strategic interest to Australia. The Gulf of Aden is of vital strategic importance, with more than 20,000 vessels travelling between Europe and the Middle East, Asia and Australia passing through the waterway every year (Liss, 2009). 2. According to the defense correspondent of Sydney Moring Herald, Jonathan Pearlman, â€Å"Australia is looking to deploy a warship to act against pirates off the coast of Somalia after winding down operations to protect Iraqs oil terminals† (Pearlman, 2009). According to Australian Air Chief Marshal Angus Houston â€Å"Australian ships and passengers regularly travelled through the waters off the coast of Somalia and benefited from the enhanced security provided by the multinational anti-piracy force† (Pearlman, 2009). 3. â€Å"The annual cost of piracy to the global economy ranges between $7 and $12 billion, by some estimates† (Ploch et al, 2011, p.ii). According to certain reports by international maritime organization, piracy is causing big threat to the lives of the people and immense damages to the shipment activities through Somali coast. Shipping cost has been increased drastically since insurance companies forced to increase the premium amount of the shipment goods insured and transported through this region. There are many reasons cited for the increasing piracy in the Somali coastal region. This paper analyses major causes of the increase in Somali-led piracy off the Horn of Africa during the past 5 years. According to the final

Friday, July 26, 2019

Global warming and the blame game Research Paper

Global warming and the blame game - Research Paper Example The major blaming debate is whether global warming is majorly accelerated by the developed countries or developing countries. It is for sure known that the problem comes from both sides of the world but determining the greatest accelerators still remains a debate in the global environment arena. To discuss this paper, the major objective is to determine whether the developed countries are the major accelerators of global warming. This leads to the discussion question, Is global warming mostly accelerated by the developed countries? The thesis that will help find the answer to this question will be: The developed nations majorly cause global warming. To support this claim, the paper discusses the various activities in developed countries that might cause global warming. One of the major causes of global warming is the emission of greenhouse gases especially Carbon dioxide (CO2) due to the huge coal burning power plants and many industries. The developed countries are the greatest emitters of these gases. The data collected from 1900 to 2004 indicates that the United States of America produced carbon dioxide that amounted to 314,772 million metric tons (The World Bank 3). Germany also produced three times as much as China that only produced 89,243 million metric tons. The World Bank report added that it is important to note that these gases stay in the atmosphere for centuries; it can take more than 30 years to remove 50% of the emissions (5). This led to increased global temperature from back in 1800s to date. The graph below shows the gradual increase in the global temperature between 1880 and 2010. Developed countries are also the greatest consumers of the environmental resources. U.S, Canada, Europe and many more nations being with less population compared to developing countries, are the greatest consumers of environmental resources such as trees, raw materials for manufacturing and in turn has led to increased

Thursday, July 25, 2019

Organizing and Delegating-Management of Organizations Essay

Organizing and Delegating-Management of Organizations - Essay Example An effective cost reduction plan should achieve results that flow from top to the bottom line of financial matters (Mosley, 2008). The plan should be designed in such a manner that its implementation does not damage the organization itself. In fact, it is argued that a good cost reduction program should focus much on damage control as it involves cutting costs. The ways of communicating these measures are equally important, especially if it concerns salaries of the employees. Cost Reduction Plan All cost reduction plans aim at reducing costs in order to improve profitability. It is apparent that by reducing expenses, profits are increased. In the current scenario, it is apparent that most of the company’s expenses go to employee salaries. With 90 percent of the company’s expenses being channeled in one department, it becomes tricky to have an effective cost reduction plan in place. In this regard, it is advisable to have a cost reduction team comprising all departments. In the beginning, the head of the cost control team should ensure that the idea of cost reduction is well discussed with the team members. In the current scenario, since cost reduction measures will mainly focus on reducing salaries of the employees, it is also advisable to have all departments represented by employees in the cost control team (Mosley, 2008). However, the meeting should be frequent, probably once in a week. This helps the effort not to lose momentum. Every meeting’s minutes should be published and availed to the chief executive and the heads of each department. The minutes should include the status of each task in the meeting. Cost reduction team members should discuss ideas in a free flowing manner. The ideas should primarily focus on the agenda of the meeting with a contribution from team members being well recorded. Since the main area of concern is salaries, it is equally important to consider a review of other areas that could also be highly contributin g to losses. For example, the cost of raw materials, electricity, travel, maintenance, etc. may as well be reviewed (Suzue, 2002). However, the next step involves cost necessity assessment. In this regard, evaluation of the magnitude of necessity of cost items identified is done. Most crucial items should be retained, but suggested reduction should be applied. Items with less magnitude of necessity should be evaluated for other options. Issues concerning salaries range from labor costs and morale initiatives to training costs. The table below indicates a cost reduction proposal that can be used to reduce cost associated with employee salaries and benefits. Item Classification Risks Decision Labor Necessary None Keep but reduce cost Supervision Necessary None Keep Overtime Necessary Morale impact Keep but reduce Coffee Unnecessary Morale impact Eliminate Department party Unnecessary Morale impact Keep but reduce Communication Plan Before any decisions are made on the measures to use in cost cutting, it is vital to consider the number of permanent employees and those that are in contract. This sets a pace in evaluating implementation negotiations (Coombs et al., 2005). The first step involves analysis of the situation that has led to seeking the option of cost reduction. This could be termed as

Wednesday, July 24, 2019

Budgeting Essay Example | Topics and Well Written Essays - 500 words

Budgeting - Essay Example man resource management which include employees’ development, compensation, rewards, and work benefits, job definition and design, and development of organizational culture. From a scientific perspective, performance management is a continuous process, which starts from the time an employee start working in an organization until the time when the employee exits the organization. Performance management is one of the things that H2O should consider placing great emphasis on as it prepares to expand its operations to the US. This is because performance management would help the company to align its HR initiatives with the US practices. That is, satisfying the needs of its human resources while ensuring that the abilities of the employees are directed towards achievement of the company’s objectives. Levensaler explains (20008) that â€Å"this is possible because performance management enables an organization to analyze how well its employees are performing on an individual basis† (p. 11). This entails analyzing how well an employee is performing in his/her current responsibilities based on the achieved results. Performance management also allows an organization to develop improvement plan. An improvement plan enables an employee to improve his/her performance, as well as prepare for future responsibilities. Furthermore, performance management would help H2O to promote cohesion between subordinates and their supervisors. Good subordinates-supervisors relationships have a positive impact not only on employees’ performance, but also in employees’ morale. In addition, performance management helps organizations to determine employees’ performance rewards which are rewarding employees depending on their abilities and achievements. Therefore, for H2O to be able to align its HR initiatives with the US practices, it should ensure that its performance management initiatives achieve the aforementioned objectives. Moreover, performance management is based on a

Tuesday, July 23, 2019

Political Speech Text Analysis Essay Example | Topics and Well Written Essays - 2000 words

Political Speech Text Analysis - Essay Example In the speech, Obama begins by raising three important questions about the state of American democracy and the notion of the ‘American Dream’. Using an affirmative tone, the new president asked the audience – ‘If there is anyone out there who still doubts that America is a place where all things are possible...’. As the first African-American ever to be elected to the highest seat of power, the president is himself a valuable answer to the question he raised. The second paragraph of the speech begins with a metaphor - ‘It is the answer told by lines that stretched around the schools and churches in numbers this nation has never seen’, which represents the millions of people who lent their voice and support to his cause and campaign. Maintaining the same affirmative posture, Obama continues to pose another question – Who still wonders if the dream of our founders is alive in our time’. He uses the word ‘dream’ to associate his question with the famous 1963 speech of Martin Luther King Jr. – ‘I have a Dream’. The president responds to the question posed by enumerating the minorities in the USA. By this, Obama shows that the ‘Dream’ for which Martin Luther sacrificed his life and fought so hard through non-violence had indeed been realized. He completes this justification by saying – ‘we have never been just a collection of individuals or a collection of red state and blue states: we are, and always will be, the United States of America’. The red and blue states used in this context represents the political parties that are usually favoured by people in the states namely the Republicans (red) and Democrats (Blue). At the end of this phrase, he calls for all citizens towards consolidation irrespective of the party they favour as they belong to the same nation. The introduction of the speech concludes with another question – ‘Who still questions the power of our

Monday, July 22, 2019

Supreme Court Essay Example for Free

Supreme Court Essay Marbury v. Madison:(1803) Judicial review In 1801, Justice William Marbury was to have received a commission from President Adams, but Secretary of State James Madison refused to issue the commission. Chief Justice Marshall stated that the Judiciary Act of 1789, which was the basis for Marburys claim, conflicted with Article III of the Constitution. Marbury did not receive the commission. This case determined that the Supreme Court and not the states would have the ultimate word on whether an issue was in violation of the Constitution. The Supreme Court judged that when the state of Georgia rescinded a land grant it was unconstitutional since it revoked the rights already granted in the contract. This was the first case to declare a state law in violation of the Constitution. . Dartmouth College v. Woodward: (1819) Contracts and State law The New Hampshire legislature amended the original charter of the college, which had been in place since 1769, to make the college more accessible to the public. The problem was that the legislature acted without consultation with the college trustee. The Supreme Court ruled that the original charter was inviolable as the charter was a contract. This decision led to a strengthening of property rights against state abridgement. McCulloch v. Maryland: (1819) Implied powers James Madison created a national bank, The state of Maryland believed this was an intrusion into states rights and attempted to tax the bank. James McCullough, who worked at the bank, refused to pay the state taxes because he believed the state had no right to tax a national bank. Marshall stated. That the bank was incompliance with the constitution and could not be subjected to state taxes. This case established the rule that states could not tax an institution of the federal government. Gibbons v. Ogden: (1824) Interstate commerce Act issue was the right to carry passengers along a canal from New York to New Jersey. The state of New York had granted Aaron Ogden the exclusive right. The federal government issued a license to Thomas Gibbons for the same route. On appeal the case went to the Supreme Court after Ogden sued Gibbons and won. The Supreme Court decided that Gibbons was right and that states cannot stop Congress regulating interstate commerce. This was a landmark case because it established federal authority over the states. This became the basis of the Civil Rights Act of 1964. Cherokee Nation v. The State of Georgia: (1831) State law and Indians The Cherokee Indians had been farming the land in the western part of the state and had established their own government. The Georgians passed laws and tried to have the Cherokee government declared null and void. The Cherokee nation brought the suit to the Supreme Court on the grounds that the Cherokee nation was a foreign entity and therefore the state of Georgia had no rights. Marshall knew that if he ruled in favor of the Indians, President Jackson would not enforce the ruling. So Marshall ruled that the Cherokee nation did not constitute a foreign nation. Thus the Supreme Court had no jurisdiction over the Cherokee nation. Worcester v. Georgia: (1832) State law and Indians in Worcester v. Georgia John Marshall invalidated a Georgia law concerning entry into the Cherokee nation. In this case Worcester, a missionary, sued on the grounds that the state had no right to control any aspect of the Cherokee nation as this would fall within the powers of the federal government. This was just one more instance of the Marshall Court increasing power for the federal government over state governments. The Marshall court attempted to protect the property rights of the Indians. Unfortunately, even Marshall was unable to keep the Indians from continually being forced off their land. . Scott v. Sanford: (1857) Citizenship and Slavery Dred Scott was the slave of an army doctor. The doctor had lived in free states and in free territories, but had returned to Missouri, a slave state, before his death. Scott sued the doctors wife for his freedom on the basis that in a free state he had been free. The Supreme Court decided that Congress had no power to forbid slavery in the territories. They also said that as a slave, Scott was not a citizen and was not eligible to sue in a federal court. This decision annulled the Missouri Compromise and the Kansas-Nebraska Act. The case centered on 3 issues: a) Was Dred Scott a citizen? b) Could Congress prohibit slavery in the territories? c) If a slave was property, then shouldnt Sanford be compensated? Scott and his family did win their freedom because Scotts new owner was the widows brother and a known abolitionist. This case was never about the freedom of Dred Scott but about the future expansion of slavery into the territories. Texas v. White:(1869) Legality of Confederate Government Policies After the Civil War the reconstruction government of the state of Texas brought suit to regain state-owned securities, which had been sold by the Confederate state legislators during the war. The defense claimed that since Texas had not been restored to the Union there were no grounds for a federal court case. Chief Justice Salmon P. Chase maintained that since secession was illegal, Texas had never left the Union. Chase said the Confederate government of the state had been unlawful so all acts carried out by the government were null and void. Therefore the state was entitled to recover the securities. Plessy v. Ferguson: (1896) Separate but equal Homer Plessy was arrested in Louisiana for riding in a whites-only railroad car. Plessy, who was one-eighth African American, appealed on the basis of the equal protection clause of the Fourteenth Amendment. The court said that so long as the facilities were equal then it was legal to racially separate. This became the impetus for segregation across the south. Swift and Company v.  United States: (1905) Defining Interstate Commerce. Swift claimed to be participating in business that was intrastate and not interstate, which he added, meant the interstate commerce act did not apply to his business. The court agreed unanimously that this was not the case and Swift was trying to create a monopoly. Armed with the Sherman Antitrust Act, Oliver Wendell Holmes said the company had a current of commerce among states. Bunting v. Oregon: (1917) Government Enforcement of 10-Hour Workday. In 1913 Oregon established a 10-hour workday for all men and women in mills or manufacturing industries. Any work beyond the ten hours was payable at a rate of time -and-a-half. Bunting, who owned a factory required his workers to work a 13 hour day and did not pay overtime. The Court was split on the issue and did not want to be seen as a regulator of wages. Eventually the court decided that overtime pay did not constitute wage regulation. Schenck v. United States: (1919) Freedom of Speech during Wartime. During World War I Charles Schenck had distributed pamphlets that said the draft was illegal. He was charged under the Espionage Act (1917). Justice Oliver Wendell Holmes rejected the argument that the pamphlets were protected by the free speech clause of the Constitution. Holmes told the court that freedom of speech could be suppressed if there is a clear and present danger, and since this happened during a time of war, there was such a circumstance. Korematsu v. United States: (1944) Legality of Japanese Internment during WWII In1942, after the Japanese attack on Pearl Harbor, President Roosevelt issued Executive Order 9066, which required the forced relocation of over 100,000 Japanese-Americans to relocation camps. The Supreme Court ruled the relocation was illegal. In1988 these people, of whom many were citizens, received compensation. tL-94l.. . Brown v. Board of Education of Topeka, Kansas: (1954) Equal protection Linda brown was denied admission to a local elementary school in Topeka, Kansas. The basis for her denial was that she was black. Chief Justice Earl Warren overruled the separate but equal doctrine of Plessy v. Ferguson. He stated that the public schools violated the fourteenth amendment condition of equal protection under the law. The defendants claimed that the inferior conditions in segregated schools hindered their development. After the ruling was made, the court declared that segregation must end. Gideon v. Wainwright: (1963) Representation by Counsel Gideon was accused of a breaking into a poolroom in Florida but he had no financial means to secure a defense. He requested a defense counsel but was refused and was forced to defend himself. The court returned a guilty verdict. This led to the Supreme Court ruling that all people were entitled to legal counsel regardless of their ability to pay for legal counsel. Heart of Atlanta Motel v.  United States: (1964) Interstate commerce In 1964 Congress tried to pass the Civil Rights Act based on its power to regulate interstate commerce. Congress believed it had the right to ban discrimination in public accommodation and in employment. A motel owner challenged the law on the basis, that he had a local business which should not be considered interstate commerce. The Supreme Court ruled that since the business gained most of its income from interstate commerce; thus, the business was liable to the rules of Article 1, section 8 of the Interstate Commerce Act. Wesberry v. Sanders: (1964) one man tine vote This case dealt ith the apportionment of congressional districts in Georgia. The voters of Georgias fifth congressional district, easily the largest district, believed that their representation was not as equal as that of other districts with less people. They argued that because the state legislators had failed to, realign the districts their vote was debased. The Supreme Court ruled that as much as possible districts should be comparable in terms of population. Miranda v. Arizona: (1966) Rights in custody Ernesto Miranda a man who had not completed the ninth grade was arrested at his home in Arizona and identified as a suspect ina rape-kidnapping case. When he was questioned about the crime Miranda maintained he was innocent, but after two hours of interrogation he signed a confession. At the trial the confession was admitted as evidence and the court found Miranda guilty. The police acknowledged that Miranda had not been made aware. of his rights during the process nor had he had access to legal counsel. While the Miranda confession was given with relatively little pressure it still violated the constitutional requirements that governed such procedures. Inthis case, the Warren court ruled that the accused must be made aware of his or her rights from the beginning. Roe v. Wade: (1973) Right to Privacy During the sexual revolution of the 1960s and 1970s the number of abortions performed illegally was unbelievably high. Inits decision the Court struck down a Texas law that made it illegal to perform abortions unless the womans life was risk. Jane Roe an unmarried mother wanted to terminate her pregnancy but she did not meet the necessary requirements. The Court sided with Roe and said that a woman had a constitutional right to privacy that extended to cover a decision whether or not to terminate her pregnancy. Bakke v. Board of Regents of California: . (1977) Affirmative Action In an attempt to get greater racial and ethnic diversity The University of California Medical School at Davis created a special category for minority students. This was the first constitutional test for affirmative action. Bakke, a white student, was rejected by the university and filed a lawsuit alleging discrimination under the Civil Rights Act of 1965. The Court said the university can use special criteria to determine which students gained acceptance so long as it did not use a quota system.

Art essay Essay Example for Free

Art essay Essay Does art imitate life – or is it the other way around? Traditionally, we have believed that art imitates life. The painter represents what he or she sees by producing a scene on a canvas. The sculptor does the same with bronze or stone. A photographer or film maker does it even more directly. A writer describes life in his or her books. This simple concept is known as mimesis. But some have questioned the one-way nature of mimesis by arguing that art also changes the way we view the world, and in fact, life sometimes imitates art rather than the other way around. The person who first articulated this belief effectively was Oscar Wilde. Speaking about the foggy conditions in London in the late 19th century, he wrote that the way we perceive them changed because of art. Referring to the wonderful brown fogs that come creeping down our streets, blurring the gas lamps and turning houses into shadows he argued that poets and painters have taught [people] the loveliness of such effects. According to Wilde, They did not exist till Art had invented them. [pic] And you don’t have to look too far to see anti-mimesis in our lives. To what extent is our outlook on life altered by ideas we read in books? The portrayal of people in films? The styles we see in fashion photography? One great example of this is the TV series The Sopranos, and how it affected both the Mafia in the USA and the FBI. Art’s influence on society: propaganda and censorship Throughout history, it has always been the case that art has the power to change society, especially when new media are used to express an idea. During the First World War, for example, movie cameras were used for the first time to record trench warfare – when the film was shown in cinemas in Britain, audiences ran out screaming. This led to the government censoring further such use of such a powerful medium. And in government censorship, and use of art as propaganda, we see how seriously governments take the effect of art. All of the major dictators of the C20th understood the power of art to influence the population. In Nazi Germany, Hitler set up the Ministry of Propaganda and National Enlightenment. It was headed by Goebbels, who made sure that nothing was published, performed, or exhibited without his approval. [pic]When this happens, you know there isn’t going to be a happy ending And what Goebbels approved, of course, only fit in with Nazi ideology and ideas. In terms of art, this meant no modern and abstract art, certainly nothing hostile to the regime, and nothing that featured images other than the stereotypical blonde-haired, blue eyed set in idyllic pastoral scenes of blissful happiness. [pic] [pic] In Stalinist Russia, there was also a keen understanding of the power of art. Art portrayed contented peasants, industrious workers, and Stalin himself. In fact, Stalin was shown god-like in many paintings, a phenomenon known as the Cult of Stalin. Just as in Germany, gigantic architectural projects expressed the power of the state. [pic] [pic] However, there is no doubt that in Russia there were greater artistic achievements than in Nazi Germany. Composers worked with fewer hindrances – as seen in the works by Prokoviev and Shostakovich, and film-makers such as Eisenstein emerged. Art’s influence on society: the trial of Lady Chatterley’s Lover But even under less oppressive governments, the artistic expression of certain ideas can be subject to control. One great example is the book ‘Lady Chatterley’s Lover’ by DH Lawrence, which was deemed offensive on many levels. In this book, Constance Reid, a woman from a progressive liberal middle class family marries a minor member of the aristocracy, Lord Clifford Chatterley, and takes the title ‘Lady Chatterley’. But her husband is injured in the First World War, confined to a wheelchair, and left impotent. Despite this, he becomes a successful writer and businessman. It is more his obsession with financial success and fame rather than any physical difficulties which come between him and his wife, and she begins an affair with their gamekeeper, Oliver Mellors. The largely aristocratic ‘establishment’ of Britain at the time – the book was published in Italy in 1928 were shocked by many aspects of the book. First, there was the fact that the book was ‘obscene’, in the way it went into explicit detail the affair that took place (see below). Second, there was the fact that a women was breaking her marriage vows, something considered far worse than a man behaving in the same way. Finally, it represented an intimate relationship between a member of the ‘lower’ classes (although it emerges during the story that Mellors is actually well-educated, and became an officer in the army during the First World War) and the ‘upper’ classes, a concept that was totally taboo in Britain at that time. The book was duly banned. [pic] But the book was republished by Penguin books in 1960. The attorney general, Reginald Manningham-Buller (dubbed ‘Bullying-Manners’ by the journalist and author Bernard Levin) had to read only four chapters to decide to prosecute Penguin books for publishing it. What annoyed him was not just the content, but the fact that the price of the book meant it was affordable to women and members of the lower classes (remember that only few women worked at this time, and husbands were generally in charge of family finances). The trial was a disaster for Manningham-Buller and the prosecution. They had failed to find any experts to support their case, in stark contrast to Penguin’s defence team, which had brought in authors, journalists, academics, and even members of the clergy to defend the book. Manningham-Buller and his team had very little idea of what Lawrence had been trying to express in his book, regularly being caught out by the superior insight of the witnesses they were trying to catch out. And although they tried to shock the jury – in his opening speech, Manningham-Buller announced: The word fuck or fucking appears no less than 30 times . . . Cunt 14 times; balls 13 times; shit and arse six times apiece; cock four times; piss three times, and so on. they were unable to prove that the book would have a negative influence on the readers it was aimed at. According to the Guardian: No other jury verdict in British history has had such a deep social impact. Over the next three months Penguin sold 3m copies of the book – an example of what many years later was described as the Spycatcher effect, by which the attempt to suppress a book through unsuccessful litigation serves only to promote huge sales. The jury – that iconic representative of democratic society – had given its imprimatur to ending the taboo on sexual discussion in art and entertainment. Within a few years the stifling censorship of the theatre by the lord chamberlain had been abolished, and a gritty realism emerged in British cinema and drama. (Saturday Night and Sunday Morning came out at the same time as the unexpurgated Lady Chatterley, and very soon Peter Finch was commenting on Glenda Jacksons tired old tits in Sunday Bloody Sunday and Ken Tynan said the first fuck on the BBC. ) Homosexuality was decriminalised, abortions were available on reasonable demand, and in order to obtain a divorce it was unnecessary to prove that a spouse had committed the matrimonial crime of adultery. Judges no longer put on black caps to sentence prisoners to hang by the neck until dead. Can we say, though, that it was art in this case that changed society, or was it an interaction between human sciences (ie, the law) and the arts (the book) that led to change? This is from the same Guardian article: †¦the message of Lady Chatterleys Lover, half a century after the trial, is that literature in itself does no harm at all. The damage that gets attributed to books – and to plays and movies and cartoons – is caused by the actions of people who try to suppress them. See: The trial of Lady Chatterleys Lover The effect of art: presentation [pic] What other piece of art has profoundly changed the way we view the world? And was it the art that did it, or the way it was used that made the impact? Use the link below to help you introduce to us an influential piece of art. Think about the type of change it wrought, for example, ethical, social, metaphysical, etc.

Sunday, July 21, 2019

A review of Bioactivation and Tissue Toxicity

A review of Bioactivation and Tissue Toxicity Kong Wei En (BP0711031415) Raymond Koh Chee How (BP0711031287) Jennie Lee Sheah Lin (BP0711031372) Prashanthini A/P Janardanan (BP0711031156) Hong Wei Siong (BP0711031194) Shalini A/P Shanmugavelu (BP0711031145) Introduction Xenobiotics are foreign chemicals in the body [1]. The human body has adapted processes collectively termed as biotransformation to excrete these xenobiotics [1,2]. Biotransformation generally occurs sequentially in two phases [1,2]. Phase I reactions add new functional groups to the parent compound while phase II reactions conjugate these new functional groups with polar groups [1,2]. The end-result of biotransformation is decreased lipid solubility, thus increasing renal excretion [1,2]. The liver is the chief site for biotransformation, [1,2]. Enzymes such as cytochrome P450 and peroxidase enzymes are responsible for biotransformation [3,4]. Occasionally, bioactivation occurs, in which the inert parent compound is modified into toxic metabolites [1,3,4]. The toxic metabolites are either electrophiles or free radicals, which interact with body tissues, subsequently causing toxicity [3,5]. Electrophiles Electrophiles are species deficient in electron pair generated through Phase 1 metabolism by CYP450 [5]. They are short-lived (with the possible exception of some acyl glucuronides) and not usually detectable in circulation [5]. Electrophiles can be generated from carbon, nitrogen or sulphur containing compounds [4]. The most frequently metabolised structural alerts are aromatic systems with electron-donating substituents and some five-membered heterocyclic [6]. Electrophiles cause toxicity through the formation of irreversible covalent bond to nucleophilic tissue components which includes macromolecules (proteins, nucleic acids and lipids) or low molecular weight cellular constituents [4]. Covalent binding generates potent and long lasting toxic effects because the covalently modified enzyme/receptor is permanently inactivated [4]. The covalent binding to DNA leads to mutation, tissue necrosis, carcinogenicity and tumour formation [4]. Mutations arise when the electrophiles escape the repair mechanisms of the cell, may be fixed and passed to the progeny [4]. If the electrophiles bind to protein, they will disturb the physiological homeostasis, leading to cell death [7]. Examples of electrophiles include epoxide, hydroxylamines and aldehydes [4,5]. Free radicals Free radicals (species containing an odd number of electrons) may be cations, anions or neutral radicals [8]. Free radicals are generally formed via NADPH CYP450 reductase or other flavin containing reductases [8]. They provide toxicity by peroxidation of cellular components. An important class of free radicals is organic free radicals such as hydrogen peroxide and superoxide anion [8]. The potential toxicity of free radicals is far greater than electrophiles [8]. Free radicals are able to produce chemical modifications and damage to proteins, lipids, carbohydrates and nucleotides [9]. If the reactive free radical is formed close to DNA then it may produce a change in the structure resulting in a mutation or cytotoxicity [9]. Protein and non-protein thiol groups are readily oxidized by many free radicals and may lead to profound changes in enzyme activity [9]. Another major pathway of metabolic disturbances is depending on covalent binding with cell components such as protein, lipid and nucleic acid to from a stable covalently bound adduct that may grossly distort structure and function [9]. Reactive free radical may also damage cells through membrane damage [9]. Examples of free radicals include hydrogen peroxide, hydroxyl radical and peroxynitrite [10]. Examples of drugs undergoing bioactivation and causing subsequent tissue toxicity Table 1: Several drugs, with their corresponding toxic metabolic pathways and the subsequent adverse effects. Drug Metabolic pathway Adverse effects Chloramphenicol Chloramphenicol is first oxidised by CYP monooxygenase into its dichloromethyl moiety [11]. Hydrochloric acid is then eliminated to produce a reactive metabolite that interacts with the Æ -amino acid of a lysine residue in CYP monooxygenase [11]. The enzymatic reaction is eventually retards over time, leading to adverse effects [11]. Apalstic anemia [12] Bone marrow toxicity [12] Acetaminophen The reactive metabolite is called N-acetyl-p-benzoquinone imine (NAPQI) [11]. Metabolic pathway 1: Acetaminophen undergoes N-oxidation to become N-hydroxyacetaminophen, which then undergoes dehydration to form NAPQI [11]. This pathway is probably uncommon as N-hydroxyacetaminophen is not a chief intermediate in the oxidation of acetaminophen [11]. Metabolic pathway 2: NAPQI undergoes a Michael-type addition with either glutathione or protein thiol groups [11]. Hepatotoxicity [11,12]. Tienilic acid Tienilic acid is oxidised by CYP2C9 to either thiophene sulfoxide or thiophene epoxide [11]. These electrophilic reactive intermediates alkylate CYP2C9, permanently binding themselves to the enzyme [11]. The enzyme is subsequently inactivated [11]. The body then produces anti-LKM2 autoantibodies against the native CYP2C9 enzyme and the modified CYP2C9 enzyme [11]. Immunoallergic hepatitis [11] Halothane Matabolic pathway 1: In hypoxic states, halothane undergoes reduction to produce the 1-chloro-2,2,2-trifluoroethyl free radical [11]. This free radical performs a radical attack, leading to the necrosis of hepatocytes [11]. The radical may also react with the Fe2+ in the CYP enzyme to form an iron ÏÆ'-alkyl complex [11]. This complex then causes the necrosis of the hepatocytes [11]. Metabolic pathway 2: Halothane undergoes oxidation to produce trifluoroacetyl chloride [11]. Liver proteins are then trifluoroacetylated on their Æ -NH2-lysyl residue [11]. This newly formed neoantigen evokes an immune response towards the liver [11]. Severe hepatitis [11] Valproic acid Valproic acid is metabolised by CYP2C9 into 2-propyl-4-pentenoic acid, also termed as Δ4VPA [11]. This metabolite can then undergo two pathways [11]. Metabolic pathway 1: CYP enzymes metabolize Δ4VPA into a reactive metabolite, which then proceeds to alkylate the prosthetic heme of the CYP enzymes [11]. Hence, the enzymes are inhibited [11]. Metabolic pathway 2: The Δ4VPA metabolite undergoes ÃŽ ²-oxidation to generate the Coenzyme A ester of 3-oxo-2-propyl-4-pentenoic acid [11]. This new metabolite alkylates the terminal enzyme of ÃŽ ²-oxidation (3-ketoacyl-CoA thiolase) by a nucleophilic attack at the olefinic terminus [11]. Hepatotoxicity [11] Troglitazone Metabolic pathway 1: The thiazolidinedione ring undergoes oxidative cleavage to produce a reactive sulfoxide intermediate, which spontaneously opens its ring [11]. Metabolic pathway 2: The phenolic hydroxyl group of troglitazone undergoes a one-electron oxidation catalysed by CYP3A to produce an unstable hemiacetal, which spontaneously opens to form a quinine metabolite [11]. The quinine metabolite then undergoes the metabolic pathway described earlier (metabolic pathway 1) [11]. Metabolic pathway 3: The unstable hemiacetal produced in metabolic pathway 2 may undego hydrogen abstraction, resulting in the production of an o-quinone methide derivative [11]. Hepatic failure Death (due to hepatic failure) [11]. Part 2: Applications of Bioactivation and Tissue Toxicity in Abacavir and Lidocaine Abacavir Abacavir (ABC) is an anti-HIV drug classified as a nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) [13]. ABC possesses a significant role in the treatment of HIV patients [13]. First, ABC is subjected to phase I oxidation to produce ABC-carboxylate, followed by phase II glucuronidation to generate the inactive glucuronide metabolite [13]. Both the glucuronide and carboxylate metabolites are chiefly eliminated in the urine [13]. ABC undergoes bioactivation to form reactive aldehyde metabolites [13]. ABC metabolism to ABC-carboxylate involves a two-step oxidation via an aldehyde intermediate (unconjugated ABC-aldehyde) which rapidly tautomerizes to the more stable conjugated ABC-aldehyde [13]. This reactive metabolite is capable of reacting with proteins to produce covalent adducts, which results in the occurrence of adverse effects [13]. The most prevalent acute ABC-induced adverse effects are the potentially life-threatening hypersensitivity reactions (HSR) that occur within the first 6 weeks of treatment [13]. ABC also possesses the potential to induce cardiotoxicity, which raised further concerns about the prolonged administration of this drug [13]. Lidocaine Lidocaine has been extensively used in the treatment of ventricular arrhythmias [14]. It is also usually administered intravenously to treat and prevent cardiac arrhythmias after acute myocardial infarction [14]. Its chemical structure is an amide with an aromatic group [15]. Lidocaine is chiefly metabolized by the microsomal enzyme system in the liver [15]. The major biotransformation pathways are oxidation and hydroxylation [14]. Lidocaine undergoes oxidative N-deethylation to form the toxic mono-ethylglycinexylidide, which is then hydrolysed to 2,6-xylidine [14,15]. Finally, 2,6-xylidine is modified to 4-hydroxy-2,6-xylidine, which is excreted in urine [14]. Lidocaine also undergoes hydroxylation of the aromatic nitrogen to form N-hydroxylidocaine and the toxic N-hydroxymonoethylglycinexylidide [14]. The active and toxic metabolites known as mono-ethylglycinexylidide and N-hydroxymonoethylglycinexylidide primarily cause neural and cardiac toxicity [14,15]. Early signs of CNS intoxication include shivering, muscular twitching and tremors of the facial muscles [15]. As toxicity is low, it is safely and extensively used to treat arrhythmias [15]. Conclusion To eliminate xenobiotics from our body, processes collectively termed as biotransformation occurs in two phases. However, toxic metabolites (electrophiles or free radicals) may be produced in processes called bioactivation, which interact with body tissues and cause tissue toxicity. The bioactivation and subsequent adverse effects of abacavir and lidocaine has been discussed in detail. References [1] Rang H, Dale M, Ritter J. Rang Dales pharmacology. 7th Edition. Edinburgh: Churchill Livingstone; 2011. [2] Dekant W. The role of biotransformation and bioactivation in toxicity. Springer. 2009; 57-86. [3] Walsh J, Miwa G. Bioactivation of drugs: risk and drug design. Annual review of pharmacology and toxicology. 2011; 51: 145-67. [4] Brahmankar DM, Jaiswal SB. Biopharmaceutics and Pharmacokinetics A Treatise. 2nd Edition. Vallabh Publications Prakashan; 2012. [5] Boyer T, Manns M, Sanyal A, Zakim D. Zakim and Boyers hepatology. Philadelphia, PA: Saunders/Elsevier; 2012. [6] Walsh J, Miwa G. Bioactivation of drugs: risk and drug design. Annual review of pharmacology and toxicology. 2011; 51: 145-67. [7] Ioannides C, Lewis DFV. Cytochromes P450 in the Bioactivation of Chemicals,Current Topics in Medicinal Chemistry. 2004; 4:1767-88. [8] Leon Shargel , Andrew Yu, Suzanna Wu-Pong. Applied Biopharmaceutics Pharmacokinetics. 6th ed. USA :McGraw Hill ; 2012. [9] Trevor F. Slater. Free-radical mechanisms in tissue injury. Biochem J. 1984 Aug 15;222(1):1-15. [10] V. Lobo, A. Patil, A. Phatak, N. Chandra. Free radicals and functional foods : impact on human health. Pharmacogn Rev. 2010 Dec; 4(8): 118-26 [11] Wermuth CG, editor. The Practice of Medicinal Chemistry. 3rd edition. UK and USA: Elsevier Ltd.; 2008. [12] Nassar AF, Hollenberg PF, Scatina J, editors. Drug Metabolism Handbook: Concepts and Applications. New Jersey and Canada: John Wiley Sons, Inc.; 2009. [13] Griloa NM, Charneirab C, Pereiraa SA, et al. Bioactivation to an aldehyde metabolite-Possible role in the onset of toxicity induced by the anti-HIV drug abacavir. Toxicology Letters. 2014; 224: 416-23. [14] Collinsworth KA, Kalman SM, Harrison DC. The Clinical Pharmacology of Lidocaine as an Antiarrhythmic Drug. Circulation. 1974;50:1217-30. [15] Johansen Ø. Comparison of Articaine and Lidocaine used as Dental Local Anesthetics. Faculty of Dentistry, University of Oslo; 2004. 25 p.

Saturday, July 20, 2019

Shaker Communities Essays -- Essays Papers

Shaker Communities During the 1800’s many utopian societies sprouted in the United States. Most of these societies blossomed and faded quite quickly, but one group did not fade away like the others. This society successfully combined their faith with the reasoning of the changing times and kept their communities going strong. They are or known as the Shakers, or more formally as the members of the United Society of Believers in Christ's Second Appearing. The Shakers were inventors and thinkers who challenged many traditional thoughts and beliefs. Even today, people marvel and wonder at the Shakers and their communities, which have survived for over two hundred and twenty years and whose influences on society still are present today. Originally, the Shakers formed out of a sect of Quakers in England that was known as the "Shaking Quakers" due to their very emotional religious services. Jane and James Wardley led the group who shook, danced, sang and spoke in tongues during services. A woman from Manchester, England, named Ann Lee joined the group in 1758. In 1770 she was arrested and spent time in jail for disturbing the peace during a religious celebration. During this time Ann had her vision of "Adam and Eve having carnal intercourse" which shaped the future of the group.1 Afterwards she came to the realization that sexual intercourse caused humankind’s fall from grace. Following her release from jail, she went forth to tell the members of the Shaking Quakers in Manchester about her vision. At this point, Ann Lee became known as Mother Ann, the leader of the Shaking Quakers. For the next four years, the group remained in England. Due to the persecution they faced during this time, they failed to attract many new members... ...x/soc257/nrms/Shakers.html (5 Mar. 2000). 3. Hillebrand ( Http://www.webzonecom.com/ccn/cults/othr09a.txt). 4. Robley Edward Whitson, The Shakers: Two Centuries of Spiritual Refection (New York: Paulist Press, 1983), 1-2. 5. David R. Lamson, Two Years Experience Among the Shakers (New York: AMS Press Inc., 1971), 10-11. 6. Lawrence Foster, Women, Family, and Utopia (New York: Syracuse University Press, 1991), 30-31. 7. Stephen J. Stein, The Shaker Experience in America (New Haven, CO: Yale University Press, 1992) 133-134. 8. Unknown, "New Release from Storey Books - Shaker Medicinal Herbs" Http://www.storey.com/news/aug0404.htm (5 Mar. 2000). 9. Unknown, "Sabbathday Lake." Http://www.shakerworkshops.com/sdl.htm (5 Mar. 2000). 10. Harlan ( Http://cti.itc.virginia.edu/~jkh8x/soc257/nrms/Shakers.html).

Friday, July 19, 2019

Bacterial Resistance Essay -- essays research papers

Bacterial Resistance   Ã‚  Ã‚  Ã‚  Ã‚  Bacterial resistance is a problem that has profoundly impacted the medical community. Bacterial resistance results when bacteria become resistant to individual antibiotics through the development of specific defense mechanisms which render the antibiotic ineffective. This problem has become evident in recent years as numerous cases have been reported in which antibiotics are not effective against the bacteria that they have fought off for years. The recent troubles with bacterial resistance have caused panic throughout the United States. The pharmaceutical industry hasn’t been producing many antibiotics because they thought that the antibiotics they had created had solved many of the problems resulting from bacterial infections. An increasing amount of attention has been given to antibiotic resistance with each passing year and experts are optimistic for the future; however, the threat of bacterial resistance exists today and is a major cause for concern.   Ã‚  Ã‚  Ã‚  Ã‚  The discovery of penicillin the 1940s proved to be the dawn of the antibiotic era. In less than two decades, major advancements had been made in the development of antibiotics. There were so many different antibiotics developed that doctors and scientists focused their attention on other problems plaguing the nation. Doctors prescribed antibiotics frequently, often when they were not even needed. According to a 1998 report by the Institute of...

Sun Also Rises Essay -- essays research papers

The Sun Also Rises The novel starts out when Jake Barnes, Frances Coyne, and Robert Cohn are dining together. Jake suggests that he and Cohn go to Strasbourg together, because he knows a girl there who can show them around. Frances kicks him under the table several times before Jake gets her hint. After dinner, Robert follows Cohn to ask why he mentioned the girl. He tells Robert that he can’t take any trip that involves seeing any girls. Robert gains a new confidence when he returns from a trip to New York where the critics praised his first novel. Women threw themselves at him, and he also won several hundred dollars playing bridge with his New York connections. He has also been seized with a desire to go to South America. He feels that he is not living his life to the fullest, and he unsuccessfully tries to persuade Jake to go with him, offering to pay for everything. Jake tells him that only bull-fighters live their lives to the fullest. But Jake just tells him that he can’t escape his misery by moving from one place to another. While sitting alone in a cafe later that evening, Jake catches the eye of a pretty girl named Georgette. Jake thinks it would be nice to have dinner with someone, so they take a cab to find a restaurant. Georgette makes a pass at him, and Jake explains that he got a wound in the war that makes it impossible for him to have sex. They agree that the war was a horrible thing, and that it never should have been fought. When they get to the restaurant, some of Jake's friends see him and invite him to a dancing-club with Georgette. Lady Brett Ashley arrives with a group of men that are wearing jerseys. Cohn asks Jake to have a drink, and Brett joins them. Cohn immediately becomes infatuated with her, and tries unsuccessfully to persuade her to dance with him. But Jake and Brett end up leaving the club together. Once they get into a taxi, Brett tells Jake that she is miserable. Jake kisses her, but she tells him to stop. They love one another, but Brett won’t have a romantic relationship because Jake can’t have sex. They go to a cafe to drink. When they get there, they meet some acquaintances, and get introduced to Count Mippipopolous. Jake leaves to return home for the ... ...ean de Luz to drop Mike off. Jake says good-bye to Bill at the train station in Bayonne. Then Jake takes a train to San Sebastian. Not long after he gets there, he gets two telegrams, one forwarded from Paris and one forwarded from Pamplona. They are both from Brett. She wants him to come to Hotel Montana in Madrid because she’s in trouble. When Jake gets to Madrid, Brett greets him with a kiss. She called Jake because she was not sure if she could make Pedro go away, and she did not have money to leave. Pedro offered her money, but she would not take it. He wanted to marry her, so she would not leave him. She left Pedro because she did not want to ruin him. She wants to go back to Mike. Brett and Jake go to a bar and have several martinis before having dinner in a nice restaurant with several bottles of wine. She begs Jake not to get drunk. She assures him that he will be all right. They get a taxi to drive around town. Jake puts his arm around her, and Brett says, "Oh Jake, we could have had such a damned good time together." Jake replies, "Yes, isn't it pretty to think so?" And that’s how the book ends.

Thursday, July 18, 2019

Media studies †Life on Mars Essay

How does life on mars (2006) use visual codes, technical, audio and narrative codes to create a sense of excitement and encourage the audience to watch. In this first episode of Life on Mars there are many different codes and conventions used to make this series instantly appealing to the audience. The episode is excellently paced and smartly directed, getting us into 1973 within 10 minutes and introducing new characters effortlessly. Sequence 1 of life on mars gets the audience instantly familiar with the genre, the episode begins with a police car chasing down a suspect which quickly shows us this is a hybrid police crime drama. The diegetic sounds of police sirens and dogs along with the non diegetic music, a heartbeat which is corresponding with Sam the detective in the police car creating suspense as we get a feel for how Sam is feeling as the heartbeat signifies his nerves also introducing the audience to protagonist Sam Tyler, these audio codes add up to create an exciting police chase which again expresses the genre of ‘Life on Mars’. Once out of the car Sam is forced to chase his primary suspect down an ally way in a council estate in the city giving the audience a feel for the setting. The music isn’t as dramatic while the chase is happening but speeds up during more dramatic parts of the chase which creates suspense. Cinema-verte is used when filming the chase which makes the audience feel almost part of the chase, this entertaining filming technique and creative use of music makes Life on Mars exciting to the audience creating enigma and encouraging them to watch on. This chase takes us up to Colin Raimes arrest bringing us to sequence 2. In sequence 2 Sam’s colleague and girlfriend, Maya, are interviewing suspect Colin Raimes. Sam and Maya facing Colin and his lawyers, which creates tension between these two sets of people. During the interview there is a close up of Colin Raimes which engages the audience creating tension and increasing the viewers curiosity as to what this suspect has done and makes them wonder has he done it or not? The diegetic recording sound in the background shows the viewers the interview is being recorded and shows the viewers the seriousness of the situation, the room is dark with little light which creates a professional mood, the dark setting is a technique used to scare the suspect in to talking, perfect for the situation. The narrative codes in this sequence reveal allot about Colin Raimes as he gets upset by the images he is being shown, we learn Colin sees a psychiatrist and his lawyers talk about how kids would throw fireworks at him on his estate. This is evidence to show that Colin is vulnerable and is possibly mad, the audience may take pity on him or take a different view on the suspect, this makes the viewers curious and increases their want to watch on. After the interview in sequence 3, Maya isn’t done with the suspect and decides to follow him on her own, only to be kidnapped. Once Maya is kidnapped Sam becomes sad and heads out looking for her, there is a close up of Sams face and he is distressed with tears running from his eyes. This visual codes will make the audience feel sympathetic towards Sam and shows us perhaps he is feeling stronger than just friendship for Maya. Sams nerves eventually get the better of him when he has to stop the car to refresh himself, standing there half-heartedly he says into himself,’ The world is a scary place’ again this shows the audience he is thinking about Maya and wants to find her increasing their sympathy for him and overall making the viewers want to continue to watch to see the conclusion. The different audio codes used express Sams feeling for Maya as the non diegetic music plays softly whilst he cries and thinks about her, this corresponds with the visual codes creating a sympathetic feel for the protagonist making the audience pity him. Sam is unexpectedly struck by a speeding vehicle which brings me to sequence four. Sam is struck very unexpectedly and this may have came as a shock to the audience, the accident is very unexpected and this is done deliberately to shock the audience as this scene is key to the viewers as it is where the storyline unfolds as after this it is based in 1973, where Sam time travels back in time. The diegetic sounds used are very impacting, when the car hits Sam, initially there is a loud sound to signify he has been hit, after this all that can be heard is silence which corresponds with how the audience will feel, as they will be shocked at what has just happened. This creates enigma and increases the viewers curiosity to keep watching and they are now introduced to how Life on Mars is going to take place. (back in time) will Sam be okay? what will happen next? are few of the questions the audience will be asking making them exciting and encouraging them to keep watching. Once Sam is hit and the audience are aware of what happened there is a close up of him laying vulnerably on the ground, this close up shot shows his eyes, wide open but yet not moving, with only police sirens and a heartbeat which is corresponding with Sams as he lays on the tarmac, creating tension and making the audience question if he is even alive. This close up then changes to a high shot as the camera slowly moves up, looking down on Sam which shows how empty the road is, no traffic just him. This suggests a change in time and expresses to the audience what has happened introducing them to 1973. These visual and technical codes all raise the audiences awareness causing them to ask questions and want to know the conclusion. Sequence five is the most important as, Sam wakes up to find himself in 1973, complete with 1970s era clothing and an 8-track playing â€Å"Life on Mars† in a car. Dazed and confused, Sam wanders back to the police precinct he works at, only to find it filled with cigarette-smoking, gum-chewing strangers he’s never seen before. The music is significant as before the crash David Bowies 1970’s song â€Å"Life on Mars† was playing on Sams ipod in the car. This is strange as he has travelled back in time to when this song was just out and extremely popular. Sams feeling are conveyed in different ways, with voices in his head from when he was a boy repeating,’ where are you?’ as he wakes up in a forest, obviously not where he was before. Creating enigma for the audience and making them aware of the time change increasing their excitement and want to continue watching. When Sam stands up in 1973, with no clue as to where he is the camera is low angled and is circling him while â€Å"Life on Mars† plays which really creates a confusing atmosphere showing that Sam does not know what is going on. This technical camera work helps to express Sams feelings and shows the audience a broader understanding of what’s going on. Everything has changed in Sams world, The set designs and costumes effectively evoke the era, as well as the grittiness of the run-down neighbourhood and police precinct. Everything feels straight out of the 70s, from the clothing to the cars to the horridly ugly decorating in Sam’s apartment. Throughout the episode, Sam hears hospital noises and doctor voices and at one point sees a person on late night TV talking like a doctor describing Sam being in a coma. Sam becomes increasingly convinced that he truly is in a coma, and that none of this world is real. he believes it is all part of his imagination. These are some of the ways in which Sam portrays his feelings to the audience during this sequence. Which allows the audience to get to know Sam and begin to have a feel for his character encouraging them to continue to watch Life on Mars. Later Sam meets a young police officer named Annie Cartwright who he begins to open up to and express his opinion and at one point tells her â€Å"I had an accident and when I woke up, I was here. Only here is 33 years in the past. Now, that either makes me a time-traveller, a lunatic, or I’m lying in a hospital bed in 2006 and none of this is real.† This quotation of what he says gives the audience insight into how he feels about the whole situation, this again allows the audience to engage with Sam and feel what he is going through, the audience will grow a certain like for Sam and this creates a sense of excitement and encourages the audience to continue to watch â€Å"Life on Mars†.

Wednesday, July 17, 2019

Opera Music

Listening to an opera house house house house is atomic number 53 of the most interesting determinate medication instruction executions you could follow through live. This 90 dainty opera I seen was tacticsed on Tuesday, November 13, 2012 and performed at 8 p. m. The name play was Wozzeck by Alben Burg and performed by the Philharmonic Ocrhestra. At the opera the person who was suppose to be the debase was ill so Kevin Beurdette took Tijil Faveyls place. The commonwealth that attended the concert varied, some plenty were older and other plurality were young. The geek of course of people that showed up to this concert was non specifically seen because most of the people that did show where dressed formal-casual.This concert had no special occasion to it plainly excessively the fact that it was a mandatory class meeting at the Disney Concert Hall. The opera had a full orchestra. During this opera operation none of the actors had costumes on nor was the stage speciali ze up for an performing show. The purviews performed were all up to the actors they memorized the play and thence improvised their acting on check off. The Doctor acted by Burdette had to unfeignedly improvise his part. Every time he came out in a scene he carried the script with him out on stage.This opera was in German and in that location were surr-titles instead of subtitles. The audience laughed during the opera and they were to form a sense of relationship with play. Since it was a play the audience only applauded when the opera was over. The play Wozzeck was a play that not washed-up by Georg Buchner and Alban Berg finished his play. This play is set back in World War I. It is a myth about soldier Wozzeck who is in sack out with a prostitute and she is the mother of his son. Wozzeck is not able to meet her needs financially, so he takes part in the doctors experiment.The experiments start to make him comprehend and hear thing. On the mean age his wife is having an a ffair with a arise major and plans to be with him. Wozzeck becomes suspicious of her and then doctor and captain tempt Wozzeck to do something about. He then starts to obtain brainsick visions of her and the drummer. So he sets forth on killing her and then he himself drowning because he wants to hide the knife far into the body of water so no one could reckon it. This tragic play is composed by Esa-Pekka Salonen at the Disney Concert Hall. It is a 3 part play that is roughly 90 minutes long.Salonen has been with the Los Angeles Philharmonic Music film director from 1992 until 2009. The play has an orchestra of fifty people and dispatch set orchestra which was the UC Berkley chamber chorus that contend outside in order to set the mood of an illusion. The characters Marie and Wozzeck had solos, during the play to each one character sang in channel of the music the texture of this play is same and polyphonic. Besides about the fact that twain main characters had solos at that place was a group of electric shaverren that came out to sing. ZacharyMimis the child of Marie had a small solo at the end of the play.The tempo in Wozzeck fluctuated as some scenes where nerve racking or some were distressing. During the play dynamic phone line was played in tune with the tempo. every last(predicate) abruptly the 2 bassoons would play rattling fast and loud and other times play really slow. The music in the play was secular and not frighten music. The opera Wozzeck was a great doing I did not go in with high hopes only because what my view of an opera was not for it. Whenever I think of an opera I think of some plentiful ladies wearing a Viking helmet and looking similar fighters.This opera was a little contrastive because each actor had a characteristic personality that was vividly seen. The captain was a crazy character, his acting placed him as one of my favorites. His interacting with Wozzeck because he would make cheer of Wozzeck for being a c razy plunger and poor. One thing that I notice about the music was that sometimes when a character would sing they would not be in tune with music but then end it in tune. The music had intensive moments that surprised me with excitement.The play was similarly frolicny because of the word choice use in order to make fun of a character. Coming to this opera was a new envision I enjoyed the performance I could not sit tacit because I was getting tired of sitting. The pot that I sat in was one of the best seats that I have had there. The sound quality that was produced was great and you could see all of what the characters where doing. Although it was a bit distracting to be looking up at the surr-scripts it was an experience I will not forget. I am definitely glad I had the chance to see an opera standardised this.

Tuesday, July 16, 2019

Moral psychology Essay

Moral psychology Essay

Psychology is a subject that is broad, so you prefer to locate a subject which allows you to adequately cover the topic.Students often cited how this fact as anunaddressed weakness in Professor Waddock’s analysis. b. The average level of moral reasoning good for the Danish auditors in the study was a p-scoreof 35.48, which corresponds to a conventional level of moral reasoning.Psychology overlaps with a total number of different branches of psychology, in addition to other areas, like linguistics.† Based on Kohlberg’s categories, this implies that many internal auditors in thesample will be heavily swayed by client preferences, and that regulatory pressure/compliance threats will be important in affecting auditors’ judgments.c. The arguments in Paper 1 assume that medical ethics can be taught, and yet the evidence inPaper 2 suggests how that many auditors who have received a business elementary school educationare still operating at very low levels of m oral reasoning. Therefore, students’expressed concerns about whether ethics can really be taught in non formal business schoolsettings.

If youre discussing a research or theory comparative study make sure you cite the informations origin.d. Students completing this whole project provided many examples of possible dilemmas. Common few examples included concerns about client pressure on difficult accountingissues, independence issues, the direct relationship between tax and audit services, andinterpersonal dynamics (including early age and gender issues, and concerns about technological how tohandle the inappropriate judgments of colleagues).In terms of plans for handling thesituation, any reasonable new plan was deemed appropriate for purposes of assigning points.Morality could possibly be part fundamental to those three, also it might be important to a single kind of evaluation than another.If the opportunity logical and also given proper encouragement to good practice a inner awareness of morality, but most private individuals will create a balanced morality to direct their day-to-day interactions keyword with their own world.

Detecting a topic for check your study can be hard, but how there are a number of methods that are first great to think of thoughts that are intriguing.Do logical not make the error of writing all of the info you know regarding a specific topic.It is important to select debatable essay topics as you want opposing points youll counter to your points.Moral values not allow people to red lead lives, but in addition provide a feeling of own satisfaction in life and inspiration.

Monday, July 15, 2019

Judaism: Its identity and position to society

Judaism is a genuine deal than a righteousness. It is the bureau of spirit of the Judaic flock. Culture, customs, ethics, and brain of egotism these atomic number 18 a infr proceeding of Judaism as practically as the opinion and the rituals of the Judaic religion. A Jew peck be delimit in to a greater extent(prenominal) than matchless(prenominal) rails. at bottom Judaic police, macrocosm Jewish is a genial of citizenship. wiz is a Jew if mavin is born(p) of a Jewish bring or has garbage down the stairsg ane a conversion. modulation to Judaism is corresponding a conferral of citizenship it gather ins champion a genus Ph on the all in allus of the passel.A individual who fits the good exposition of a Jew is accepted as a blighter Jew by the Jewish company. til flat if a Jew does non bundle the sacred spirits of Jews and does non go in in the customs and practices of Judaism, matchless is stock-still con grimacered a Jew if he or she fits the legitimate definition. whiz could decide a Jew sacredly to the ghostly beliefs and practices of Judaism. A Jew is matchless takes in the 1 beau ideal, motive and headwaiter of the Universe, the perfection with whom the plenty Israel suck in a fussy family. umteen Jews call up paragon chose them to be his muckle.They travel on the laws that god revea guide to Moses. The cristal Commandments ar the ab ascend on authorized of these laws. In antediluvian clock the Jews were the except quite a little who godliness a single, scoop shovel paragon, and the tot several(prenominal)(prenominal) in ally community who faithed without animal(prenominal) images of divinity fudge. The Jews were resented by former(a)(a) mountain for non take parcel in the worship of all gods. This guide to the thrill that Jews were antihumanitarian, since overlap gods was considered to be an act of intimacy and universalistic annoyance for a n oppositewise(prenominal) large number.When Christianity re come forwardd the ir spectral religions of antiquity, the emeritus misinterpret of Jews did non crack out. Added to it was the wrath that the Jews, rescuer avouch population, has not draw Christians. Jews were protect under Christian law entirely were cut back in galore(postnominal) instructions. The laws in Christian lands called for Jews to be scummy and contemn in secern to boost Jewish conversions to Christianity. When Jews did not veer they were imp distributively of self-command or un ignoreny blindness (Wylen).Judaism teaches that beau ideal is the God of all serviceman and that He wants all people to aid Him by life-time their remains the flair He wants. The guidelines for this life-style are puzzle down in the Noachide Laws, the elementary cloth for a incorrupt and spiritual life. They believe that every close tobody is tout ensemble go off to lease whether to do good or wicked for God is al unitedly free people to do as He wishes, so are humans. Jews get wind any religion which upholds the Noachide Laws as an entertainable way for non-Jews to take to heart God.This does not fee-tail that they agree with everything that sweet(prenominal)wise religions teach, just that they can identify some religions as pointing out a path to God. For this reason, Jews do not define the take aim to transform other people to their religion. In particular, Jews sleep with that Islam teaches plain monotheism and that Muslims consecrate a inexorable theology that upholds the principles of the Noachide Laws. The alike(p) whitethorn be give tongue to of the Sikh religion. Jews contrive ever been less original rough Christianity.Although they recognise Christianitys eminent good principles, they flavor precarious round the Christian belief that deliverer is God. They are in addition upset nearly the put on of images and icons in Catholic and Jewish-Orthodox worship. They impression that this comes alternatively shut down to idolatry. Nonetheless, Jews nonplus continuously whap a circumscribed birth with Christianity and Islam. Rabbi Judah Halevi, a twelfth- coke scholar, set forth Judaism as the plant of the tree and Christianity and Islam as the branches, since by these religions, millions of people pack come to worship the one God (Forta).At the arise of the ordinal nose candy, a tendency of interfaith confabulation in the midst of Jews and non-Jews served as a long suit that facilitated the changes upon conflicts in religion. Although in that location had been some obstructor along the attend to, the interfaith discourse helped to germinate a break up affinity in the midst of Jews and non-Jews in the States. As a end point it came into cash advance of the eudaimonia of the Jewish community in America.This interfaith dialog took place in America in 1893 when the foundation fanta n of Religions (WPR) convened in loot delivery together Protestants, Catholics, classic Orthodox Christians, Jews, Buddhists, Hindus, Bahai, Muslims, inherent Americans and re pictureatives of other faiths as well. It offered Jewish religious leaders such as horse parsley Kohut, Isaac M. Wise, Kaufmann Kohler, Emil G. Hirsch, and Marcus Jastrow, an opportunity to present their views to a non-Jewish hearing and make a type for Judaism (Kaplan).The bulk of Jews, curiously in nitrogen America, resided in religiously pluralistic communities where people of diverse backgrounds and faiths, including numerous who had themselves experienced religious persecution, live side by side. possibly for this reason, they matte up more at ease interacting with Christians than Jews did in more or less split of the creation so much so that we know of Jews and Christians who conjugated forces in business, witnessed each others documents, and lovingize in each others homes (Bernardin i and Fiering). all over the century saucilyly discoveries, new methods of manufacture, new social conditions seduce changed peoples way of sustenance and cerebration closely the world. For Jews, this has eternally created the train to reapply the halakhah (Jewish religious law) to changing conditions for nourishment by halakhah is necessity for Jews to take on their part of their covenant relationship with God.During this century advances in technology induce led Jews to bone up questions which could not fork over been perspective of in earliest times questions rough the procedure of change electrical political machinery on Sabbaths, whether information processing system hacking is theft, whether foster beget is permissible, whether a mortal on a life support machine is live(a) or dead. To change rabbis to solvent this questions, street smart commentaries ready been added to the Shulchan Aruch (written record of halakhah), and whole books concer n with ad hoc topics of halakhah are now cosmos published. The keep reapplication of halakhah is an ongoing process (Forta). industrial plant CitedBernardini, Paolo, and Norman Fiering. The Jews and the blowup of atomic number 63 to the West, 1450 to 1800. Berghahn Books, 2001.Forta, Arye. Judaism. Heinemann, 1995.Kaplan, Dana Evan. The Cambridge henchman to American Judaism. Cambridge University Press, 2005.Wylen, Stephen M. Settings of silver-tongued An mental hospital to Judaism. Paulist Press, 2000.